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In adipose tissue, inhibition of NNMT suppresses de novo lipogenesis, normalizes fat content, and improves insulin sensitivity 2-3

Meanwhile, NNMTi treatment significantly increased energy expenditure in mice, an effect closely related to elevated NAD levels following NNMT inhibition

Experimental studies suggest copper peptides may influence communication between fibroblasts, growth factors, and extracellular matrix proteins, making AHK-Cu a valuable research model for investigating how local tissue environments regulate regeneration, structural integrity, and cellular adaptation

The copper complex gives reconstituted GHK-Cu a characteristic blue tint, which serves as a visual indicator