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Chronic stress and short-term modern life-like stress upregulates AD severity in 3xTg-AD mice, an animal model of AD (Baglietto-Vargas et al., 1995)

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However, Serum bilirubin concentrations mild increases, such as those in patients with Gilberts syndrome (GS, a benign form of unconjugated hyperbilirubinemia), as well as levels in the upper quartile of the currently accepted physiologic serum bilirubin range, have been reported to be negatively correlated with a wide range of disorders within the human body