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doi: 10.1146/annurev.immunol.20.083001.084359 199 RosenbergerKDerkowKDembnyPKrgerCSchottELehnardtS

Long-range Coulomb interactions were handled using the particle mesh Ewald summation method (PME) 54 by setting the mesh spacing to 1.0

This isnt first-line or as effective as prescription meds, but some find it helpful for tasks requiring sustained mental effort (e.g., studying)