To conduct the study, 24 rats were randomly divided into four groups: quercetin supplementation, exercise, a combination of quercetin and exercise, and a control group, with six animals in each group
O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T et al
What the clinical trial evidence shows Mounjaro (tirzepatide) ~22.5% average body weight lost at 72 weeks ( SURMOUNT-1, 15mg) Wegovy (semaglutide) ~14.9% average body weight lost at 68 weeks ( STEP-1 , 2.4mg) Saxenda / Nevolat (liraglutide) ~5-8% average body weight lost at 56 weeks ( SCALE trial ) For context, prior to GLP-1 medications, the most effective non-surgical weight loss intervention available was a combination of intensive lifestyle modification and Orlistat , which typically produces 5 to 8% weight loss
Here is what each dose looks like at 5mg/mL: Notice how doses from 1mg through 5mg all fall neatly within the range of a single 1mL insulin syringe