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Many applications of Cerebrolysin in the United States are considered investigational or off-label

A novel gastric pentadecapeptide bpc 157 with different beneficial activities and anticonvulsant effect interacting with gabaergic system could improve diazepam efficacy coadministered (10 microg/kg, 10 ng/kg i.p.) with diazepam (5.0 mg/kg i.p.) twice daily for 10 days, since diazepam chronic medication would otherwise predispose for diazepam- tolerance/withdrawal development (shorter latency to convulsion after convulsant)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 173.Benchrih R, Buekers J, Demoury C, Martins C, Purece A, Thomsen S, Waegeneers N, Clercq E, Devleesschauwer B