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2 A separate 2-week RCT testing three GlyNAC dose levels in 114 healthy older adults found good tolerability but no significant improvement in the primary endpoint (GSH:GSSG ratio) in the full study population, highlighting that responses may depend on baseline oxidative stress levels and study duration

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In mouse models of DMD, it has been found that IGF1-LR3 and other IGF-1 derivatives are capable of counteracting the negative effects of myostatin to protect muscle cells and prevent apoptosis