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Activated MZF1 induces expression of the lysosomal cysteine cathepsins B and L [47, 48] and several other cancer relevant genes [46], and interestingly also the expression of cholesterol transporter NPC1 leading to metabolic switch from cholesterol synthesis to cholesterol uptake and linking invasiveness to cholesterol uptake [7]

OMalley et al., 2000

Here, we demonstrated Pyxis performance in monitoring a two-week bioprocess that produced the NIST monoclonal antibody (mAb) reference standard utilizing Chinese Hamster Ovary (CHO) cells