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Briefly, in neoadjuvant settings, preoperative EsCu@NPs reduce tumor burden, decrease minimal residual disease, curb postsurgical recurrence and spontaneous lung metastasis, translating into prolonged survival

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10.1161/01.ATV.20.11.2336 20

The G allele (our reported effect allele, odds ratio = 0.546) is protective, whereas the C allele is associated with a higher risk of the vomiting side effect (odds ratio = 1/0.546 = 1.83)