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In general, ECs are connected side-by-side through transmembrane adhesion proteins [37], including vascular endothelial and neural cadherin at adherent junctions [38, 39], occludin [40], and members of the claudin family [41], as well as the junctional adhesion molecule (JAM) family at tight junctions [42]

The cleavage-resistant mutant NDUFS1 D255A decreases ROS formation and delays the loss of plasma membrane integrity (Ricci et al., 2004), suggesting cI inhibition as an accelerator of apoptosis

We also observed a reduction in IL-6 expression and an increase in IL-8 expression after FOXO4-DRI treatment

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