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In addition, carnitine can also activate glucocorticoid receptor (GR) and regulate glucocorticoid- responsive genes through this mechanism, playing a role in glucocorticoid regulation [81], and reducing glucocorticoid-induced muscle atrophy in patients with pemphigus [82]

conducted a Phase I dose-escalation trial of oral DCA in adults with recurrent malignant brain tumors to assess safety, tolerability, and pharmacodynamics