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The combination may produce greater vascular effects than either component alone, though this synergistic hypothesis requires further clinical validation

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In some embodiments, the formulations or compositions described herein have a pH between about 5 and about 8, or between about 6 and about 7, or between about 6.5 and about 7, or between about 5.5 and about 7.5, or between about 7.1 and about 7.7, and have a concentration of active pharmaceutical ingredient between about 50 and about 80 mM

The Guardian has been monitoring WhatsApp and Telegram groups promoting substances such as retatrutide a medicine unlicensed in the UK