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465,466,467 Moreover, addiction build-up seems to be linked to astrocytic NMDA receptors, such that deletion of the NR2C subunit specifically from astrocytes potentiated extinction of cocaine preference memory

Alternatively, it can be inhibited by non-specific agents: diamide (a thiol-oxidizing agent), N-ethylmaleimide (a thiol-alkylating compound) and butylhydroperoxide [25]

Mitochondrial ROS sources in diabetes As outlined above, the majority of molecular oxygen is processed by mitochondria involving four-electron reduction of dioxygen to water molecules