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We mostly get our dietary B12 sources from meat, as well as milk and milk products

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On the one hand, B6 can decrease high homocysteine blood levels that may increase the risk of Alzheimers ( One study in 156 adults with high homocysteine levels and mild cognitive impairment found that taking high doses of B6, B12 and folate (B9) decreased homocysteine and reduced wasting in some regions of the brain that are vulnerable to Alzheimers ( However, its unclear if a decrease in homocysteine translates to improvements in brain function or a slower rate of cognitive impairment

Others report reduced potency after freeze-thaw cycles