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Epithalon protects against post-ovulatory aging-related damage of mouse oocytes in vitro

Everolimus, an mTOR signaling pathway inhibitor typically used in tumor-targeted therapy, inhibits the mTOR3EBP4 axis, reduces GPX4 expression, and acts synergistically with RSL3 or erastin to induce ccRCC cell ferroptosis (145)

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Potential risks and contraindications Given the limited understanding of DSIPs mechanisms and effects in humans, certain risks and contraindications must be taken into consideration: Unknown long-term effects : The long-term safety of DSIP has not been well-established, and the potential risks associated with chronic use remain unclear