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[9] With the standard regimen, we do not expect any liver issues or nerve issues

Polymorphisms in various genes involved in vitamin B 12 metabolism, including the genes encoding the intrinsic factor-cobalamin receptor (60) and the holo-transcobalamin receptor (61), have been associated with increased NTD risk in some studies

Additionally, those with liver or kidney disorders might find the increased metabolic activity induced by these injections to be problematic, as these organs are crucial in processing the substances in the injections

Rather than targeting hormones or appetite pathways, it works inside the cell itself blocking an enzyme called NNMT that sits at the centre of how fat cells manage energy