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3.Hyperkalemia Hyperkalemia is a pathological condition characterized by an excessively high potassium concentration in plasma, exceeding 5.5 mmol/l

LPS activates NF-B signaling through the TLR4/CD14-MyD88-dependent pathway, inducing excessive production of pro-inflammatory cytokines such as TNF- and IL-6, triggering systemic low-grade chronic inflammation (93)

The demonstration of this enzyme decrease in relation to non-structural cardiac arrhythmias and without other explicit pathogenic mechanisms, at ayoung age, allows an appropriate correction (of oxidative stress)

Variants in genes such as PNPLA3 , TM6SF2 , MBOAT7 , and GCKR have been linked to altered hepatic lipid metabolism, fibrosis susceptibility, and disease severity