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Ocaliva, a farsenoid X receptor agonist, won the FDAs accelerated approval for PBC in May 2016

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Plants contain B12 but not attached to a protein, so it is not bioavailable to humans in this state

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doi: 10.1681/ASN.2016080816 116 AurielEKliperEShenhar-TsarfatySMoladJBerlinerSShapiraIet al

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