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A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes

Subcutaneous Injection This is the gold standard for bioavailability

10.1016/J.FREERADBIOMED.2010.02.024 138 OgawaK.SunJ.TaketaniS.NakajimaO.NishitaniC.SassaS.et al (2001)

Preclinical Observations Findings observed in murine studies include: Endurance capacity: Increased treadmill running time and distance Mitochondrial function: Enhanced respiration and ATP production in muscle Cardiac metabolism: Improved fatty acid utilization in models of heart failure Renal function: Reduced mitochondrial dysfunction and inflammation in aging kidney models Metabolic profile: Improved glucose handling in metabolic syndrome models These results are limited to animal models using intraperitoneal injection