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[175] reported that after treatment of rat primary neurons with methotrexate, a folate antagonist, the levels of PP2A methylation decreased and phosphorylated tau, APP, and -secretase were increased

One case report showed that a 35-year-old man who took 160 mg of garcinia cambogia three times a day for five months experienced liver failure ( Additional research in animals showed that garcinia cambogia may increase liver inflammation and decrease sperm production ( Finally, another case study reported that a woman developed serotonin toxicity when taking garcinia cambogia with her antidepressant medication ( Nevertheless, the most common side effects of garcinia cambogia include headaches, rashes and digestive issues ( Keep in mind that most of the research on the safety of garcinia cambogia has been done on animals or reported in single case studies

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J., Sutherland, G