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This study develops a compound, JMF4073, inhibiting thymidylate (TMP) and cytidylate (CMP) kinases, aiming for a new therapy against TKI-resistant CML

In this case, only 10% of the homocysteine pool is catabolized through the CBS transsulfuration pathway

Mass spectrum: the MS spectrum confirms exact molecular identity

Over the extended FY2007-2012 period, during which CPP and then CRP were implemented, more than 100 AF STTPs and SMTPs used about $92 million in CRP/CPP funding but also attracted almost $340 million in additional funding, including $152 million from AF acquisitions offices and a further $54 million from industry sources (see Figure 4-3)