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He was depressed for a year after production wrapped, and unhappy with a body ravaged by a crash diet that got him down to 130 pounds

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You can tune its puffing frequency, intensity and intervals and then observe what happens as the smoke is fed from the machine and passed through the airspace of the small airway chip. The lung airway chip technology is just the latest in a series of organs-on-chips microengineered cell culture devices that are sweeping the medical research world