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It should be used within 14 to 30 to maintain its effectiveness

Casein kinases are a broad family of serine/threonine kinases involved in diverse cellular processes, including signal transduction, circadian rhythm regulation, and metabolic pathways 68,69

Similar to the transcriptomic changes observed in the hypothalamus, we found that the conjugate prompted transcriptional patterns enriched for functional terms associated with synaptic transmission, including postsynaptic specialization and neuron-to-neuron synapse in the brainstem (Extended Data Fig

Acknowledgments This study was made possible by funding from National Institutes of Health R01AR060366 & R21AI094377