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ROS-induced mitochondrial dysfunction and DNA damage, along with the inhibition of key redox transcription factors such as Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) may contribute to the persistence of symptoms in both ME/CFS and Long COVID (Jarrott et al., 2022)

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A number of studies have looked at increasing glutathione levels in people with CF to improve lung function.[ref] Related article : Cystic fibrosis: How to check to see if you are a carrier of a CFTR mutation Alcohol: Long-term or heavy alcohol use depletes glutathione levels in the liver, causing alcoholic liver disease

doi: 10.1080/15502783.2024.2419388, 24