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Materials and methods Animal models In these studies, APOE-TR mice were housed in groups of up to four under standard laboratory conditions at 23 1C, 50 5% humidity, with a 12-h light/dark cycle and access to food and water ad libitum

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Relevantly, many patients tend to receive only a partially efficacious treatment due to lack of awareness of the disorder.112,113 Thus, all patients with CVS are recommended to have an individualized treatment plan for improving results (Table 3).114 Treatment protocol for patients diagnosed with CVS in the emergency room CVS: Cyclic vomiting syndrome