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Here Is What the Research Actually Says

Food and Drug Administration (FDA) evaluates investigational compounds through a structured review process that typically includes preclinical research, Phase 1, Phase 2, and Phase 3 clinical trials

A common scenario: you think you reconstituted at 10 mg/mL but actually used 5 mL instead of 6 mL of water, creating a 12 mg/mL solution

As a side note, the observed modest response for the DMSO control was also incorporated into the model to take into account that a minor part of the pathway activation observed under the experimental conditions used is due to DMSO rather than DEM (see Supplement)