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In parallel, the effect of the drugs were simulated using an adapted version of the singleGeneDeletion of the COBRA toolbox [28] (Drug Deletion function): Therefore, DrugBank v5.1.3 [29] was mined to identify 1175 drugs inhibiting metabolic genes (genes present in Recon 2.04) and their targets that were then used as input for the Drug Deletion function
Common side effects include injection site reactions such as redness, swelling, or discomfort, temporary nausea, occasional headaches, and fatigue in some users
Free Radic Res 50(2):143149 Seibt TM, Proneth B, Conrad M (2018) Role of GPX4 in ferroptosis and its pharmacological implication
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