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By the early 1970s, RJ Reynolds and Philip Morris knew of a market for low-nicotine cigarettes, especially for smokers who want to quit. 3 A 1987 Philip Morris analysis identified this market as having the highest potential for growth, with concern for a less enjoyable product which will be easier to give up, and finally quit. 3 Philip Morris estimated the potential market share of a free standing de-nicotinised cigarette brand at 1.5% to 2% or 912 billion units. 3 In the 1990s, Philip Morris released reduced-nicotine cigarettes (e.g., Benson & Hedges De-Nic, Next, Merit De-Nic), 4 yet failed to promote them as safer
In 2010, 300 smokers who expressed no desire to quit smoking agreed to try e-cigarettes
Headache 60(10):24952507 [DOI] [PubMed] [Google Scholar] 16.Wahbeh F, Restifo D, Laws S, Pawar A, Parikh NS (2024) Impact of tobacco smoking on disease-specific outcomes in common neurological disorders: a scoping review
