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TCM has made remarkable achievements in the treatment of many mountain sicknesses

\n\n\n\n The core mechanisms angiogenesis stimulation through VEGF and VEGFR2 upregulation, nitric oxide pathway modulation, growth hormone receptor sensitization, mTOR pathway interaction, and cytokine regulation provide a coherent and plausible biological framework for understanding the diverse effects observed across species and tissue types in animal studies

203 Furthermore, in an 18-month clinical phase 3 trial (NCT02548351), 23% of the patient cohort who received OCA achieved a reduction of NAS by at least one score without worsening fibrosis compared to 12% (37/311) in the placebo group, indicating that OCA improved inflammation and fibrosis in patients with NASH

Siller et al., 2015