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Our data indicate that a deficiency in cortistatin accelerated and aggravated injury-induced sciatic nerve dysfunction and subsequently increased pain hypersensitivity, and that treatment with cortistatin, once the early cellular and molecular inflammatory events occurred, ameliorated both pathological processes without influencing the early inflammatory pre-reparative context

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An effective warm-up for adductor protection should include general cardiovascular activity, dynamic hip mobility drills, and sport-specific movement patterns at gradually increasing intensity