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doi: 10.3389/fimmu.2022.826889 Received 01 December 2021 Accepted 21 January 2022 Published 18 February 2022 Volume 13 - 2022 Edited by Thomas Rogers, Temple University, United States Reviewed by Maryna Skok, Palladin Institute of Biochemistry (NAS), Ukraine

Protein concentrations of secretome samples were determined using the Lowry assay method using bovine serum albumin (BSA) as an internal control 34

Unfortunately for smokers, the cadmium in tobacco displaces zinc resulting in smokers having lower levels to support their health