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Read the full Spearmint Leaf Extract + Acetaminophen, Caffeine, Codeine interaction Chamomile Flower ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate Interaction Summary Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes

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