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Collection of an anomalous X-ray diffraction set showed a single anomalous peak in the SA binding pocket (Supplementary Fig

Marked anisocytosis is often noted (reflected as a wide red blood cell size distribution on the electronic counter) because of the coexistence of large polychromatic cells and contracted cells, some of which can be frankly classified as spherocytes

[67] Additionally, hCDR1 improved cognitive behavior and brain pathology in lupus mice [68] and downregulated the expression of the indoleamine 2, 3-dioxygenase (IDO) gene, which is increased in SLE patients

Similar to RMT, the BBB entry occurs with an invagination of cell membrane holding the bonded molecule, followed by endosomal formation and transport from the luminal to the abluminal side, and finally with the exocytosis of the cargo (Figure 3E