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In parallel, traditional herbal formulations like Yijung-tang exert prebiotic-like effects, selectively enriching beneficial microbial taxa and promoting brown adipose tissue thermogenesis (Khakisahneh et al., 2023)

In the cerebellum, which is increasingly recognized for its contributions to ASD core symptoms (DMello and Stoodley, 2015), BTBR mice show increased NFB and iNOS expression as well as lipid peroxides, indicative of increased oxidative stress (Nadeem et al., 2019)