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According to Lee and colleagues, dietary restriction for 4 weeks in rodents resulted in increased BrdU- and NeuN-positive cells in the dentate gyrus, which indicates an increase in proliferation and neuronal differentiation, respectively [176, 177]

Clinical Comparison Dosing & Administration Both peptides are most commonly administered intranasally because this route provides efficient central nervous system delivery through the olfactory pathway while bypassing first-pass metabolism

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