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Dural afferent transducers such as acid-sensing ion channels (ASICs) and transient receptor potential cation channel (TRPV) subtypes are significant in migraines pathogenesis

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Meyer AJ, Hell R

Intestinal barrier dysfunction and dysbiosis can lead to translocation of bacterial lipopolysaccharide (LPS) and gut-derived toxins into the systemic circulation, triggering systemic low-grade inflammation ( Traditional nutritional management of DKD has primarily focused on single-nutrient interventions such as protein restriction, glycemic control, and blood pressure management