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Do not use in individuals under 18 years of age

In a chronic stress-induced IBS model, triptolide reduced levels of MDA and supported the endogenous antioxidant defense system, which included elevated levels of SOD and CAT

Activating the immune system , leading to inflammatory responses throughout the body

To test whether this was unique to this single chemotherapy agent, we also repeated the same experimental design in animals that were instead treated with cisplatin (CDDP, 5 mg/kg), which is also associated with ovarian toxicity (Bildik et al, 2015