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During curing, several key changes occur: a loss of moisture content of approximately 80% (essential for making the leaves lighter and ready for fermentation), breakdown of sugars and nicotine, oxidation, and a change in color from green to brown [1]

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In a statement, Greg Burke said: "The motive is very simple: the Holy See cannot be cooperating with a practice that is clearly harming the health of people." Citing World Health Organisation (WHO) statistics, Mr Burke said smoking was to blame for upwards of seven million deaths worldwide every year

Both of these activate our reward pathways in the brain and lead to nicotine users wanting to achieve that response again and again, he explained