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Impact of heavy alcohol consumption and cigarette smoking on sperm DNA integrity

Replenishing them helps support cellular repair, healthy metabolism, and overall vitality

The hallmarks of cellular senescence, e.g., the appearance of senescence-associated -galactosidase (SA--gal) and heterochromatin foci (SAHF) as well as the increased expression of cell cycle inhibitor proteins, i.e., p16, p21, and p53, are also common markers of senescent immune cells, especially in Teff cells [154,155,156]