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For Cagri:AMY 3 R:G s , histidine side chains were predicted in the tautomeric state except H223, H302 (CTR), H18 (Cagri), H97 (RAMP3), H142, and H183 (G), which were modelled as tautomer

Per protocol analysis In addition to a standard per protocol analysis, we will use instrumental variable analysis in an attempt to estimate the true effect of cobalamin had it been given to all women in the scheduled doses and intervals

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