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First of all, its important to note that the Food and Drug Administration (FDA) does not review or approve dietary supplements for how safe or effective they may be (though brands are prohibited from marketing products that are adulterated or misbranded. Vitamins will have a date on the label, but it doesnt mean that they are automatically expired on that day

The pathogenesis of MASLD is thought to include inflammation and oxidative stress 50 and this could in theory accelerate the turnover and degradation of vitamin C, leading to increased oxalate synthesis 51

Enzymatic activity dysregulation of CBS has been frequently linked to aberrant redox homeostasis