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GLP-1 Agonists and the Anti-Aging Case GLP-1 agonists were not originally designed as anti-aging interventions

GLP-1s may help with OA by: Reducing overall inflammation Protecting cartilage in your joints Helping people lose weight takes pressure off the knees and hips Making walking and movement easier over time Studies found that GLP-1 and SGLT2 medicines may lower the risk of needing a knee replacement (for OA), though results varied

Biomarkers 14(7):486492 Li X, Mortensen B, Rushfeldt C, Huseby NE (1998) Serum gamma-glutamyltransferase and alkaline phosphatase during experimental liver metastases