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Scientists at The Scripps Research Institute (TSRI) have developed a vaccine that blocks the pain-numbing effects of the opioid drugs oxycodone (oxy) and hydrocodone (hydro) in animal models

Transl Res 164(4):302311

Cinnamon reduces inflammatory response in intestinal fibroblasts in vitro and in colitis in vivo leading to decreased fibrosis

If peptide-based approaches can provide meaningful benefit at lower cost and with fewer side effects, that combination would make them attractive as either standalone or adjunctive therapy