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doi: 10.1016/0736-5748(91)90071-s

2 Preclinical evidence and mechanistic studies This section summarizes the key in vitro and in vivo findings from preclinical studies of major classes of natural metabolites from TCMs with cardioprotective effects, and discusses the key molecular targets and pathways by which these natural metabolites exert their cardioprotective effects

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Researchers on aggressive weight loss protocols who are also combining these compounds should be particularly vigilant