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Importantly, folic acid should not be given alone before B12 deficiency is excluded or treated, as this can mask anaemia while allowing neurological damage to progress

Potential theoretical benefits include: Body composition considerations : Tirzepatide promotes significant fat loss through appetite suppression and metabolic effects, while sermorelin might theoretically support lean muscle preservation through growth hormone stimulationpotentially mitigating the muscle loss sometimes observed with rapid weight reduction

However, drug use and unhealthy diet lead to microbial dysbiosis, triggering metabolic disorders and adversely affecting kidney health ( Figure 2 ) [24, 36]

Anything above the treatment line should be treated with N-acetylcysteine since there is a risk for possible hepatotoxicity