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No lethal dose has been established in animal studies, and the peptide appears to have wide safety margins

Eosinophils were recognized to contribute to the control of bacterial infections (Bohrer et al, 2021

Excessive mitophagy or elevated mitochondrial biogenesis disrupts the delicate balance of mitochondrial homeostasis, ultimately leading to cell death or necrosis in the case of mitophagy [42]

(4) A Bian, Y Ma, X Zhou, Y Guo, et al (2020) Association between sarcopenia and levels of growth hormone and insulin-like growth factor-1 in the elderly BMC Musculoskeletal Disorders volume 21, Article number: 214 (2020)