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Since chronic and/or overaccumulation of cholesterol are known to be cytotoxic, care should be taken for the future translational applications of current research

Am J Clin Nutr 2006;83(6 suppl):1505S19S

Emerging evidence implicates programmed necrosis (necroptosis), pyroptosis (gasdermin-D pore formation) and ferroptosis (lipid peroxidation driven by iron accumulation) as additional contributors, implying multiple, drug-specific death executors [72, 79, 84,85,86]