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Second, informative injury models need to mimic the injuries seen in sporting environments (Wall and Shani, 2008), yet most brain injury models create focal hemorrhagic cortical lesions caused by direct impact to the skull or exposed brain (Xiong et al., 2013), while the human concussed brain is more commonly associated with distributed white matter alterations (Benson et al., 2007

However, examples of specific haptenation of deeply buried residues of very low abundant proteins were detected in the same study

Christiano, a professor of dermatology and genetics at Columbia University Medical Center in New York