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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Razmara A., Duckles S.P., Krause D.N., Procaccio V

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They believed it could provide a way to improve the control of diabetes

Mechanistically, CRC cells with high levels of dual specificity phosphatase 18 (DUSP18) stabilize the transcription factor upstream stimulatory factor 1 (USF1), which upregulates SREBF2, thereby increasing lanosterol biosynthesis (a substrate of CYP51A1) and its release into the TME