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This anti-inflammatory molecule can repress the pro-inflammatory gene expression while blocking the phosphorylation of the inhibitory factor I-kappa B (IkB)

[DOI] [PubMed] [Google Scholar] 63.Rameshrad M., Razavi B.M., Hosseinzadeh H

Lyakhovitsky A, Aronovich A, Gilboa S, Baum S, Barzilai A (2019) Alopecia areata: a long-term follow-up study of 104 patients

The primary outcome of the double-blind phase was the change from baseline in the score of the MDS-UPDRS part III and showed a statistically significant difference in favour of opicapone of 2.2 points less worsening at month 6 (p = 0.01) without a difference in UPDRS IV motor complication scores