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However, ICIs have shown limited efficacy in treating PDAC, predominantly because of the hostile TME characterized by fibrosis, hypoxia, and immunosuppression [148]

Methods: Databases including PubMed, Scopus, and Embase, Web of Science, and Google Scholar were searched up to June 2023

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A growing body of evidence suggests that various environmental factors influencing early neurodevelopment contribute to the etiological heterogeneity of ASD